DOSAGE
MICRODOSING
Days On, Days Off…
Microdosing is all about keeping it subtle and sustainable, so you’re not tripping but just getting a little boost in mood, focus, or creativity. A solid schedule a lot of folks swear by is the Fadiman protocol—named after this amazing researcher, James Fadiman. It’s simple: one day on, two days off. So, you’d take a gummy (or part of one, more on that in a sec) on, say, Monday, then chill on Tuesday and Wednesday, then dose again on Thursday, and so on. That’s like 2-3 doses a week, which gives your brain a breather and helps avoid building tolerance.
Another option some people like is the Stamets protocol—that’s 4 days on, 3 days off (like dose Monday through Thursday, then take Friday to Sunday off). It’s a bit more frequent, but still gives you a reset.
I’d say start with Fadiman’s one on, two off to keep it light and see how you feel, since it’s less intense for beginners. After your comfort level with the effects are dialed in, I would recommend jumping up to the Stamets method for ongoing strategy.
Whole Gummy or Partial? Easing In…
Your gummies are a pretty standard microdose size—usually, a microdose is 0.1g to 0.3g, so you’re in the ballpark. But here’s the deal: everyone’s body and brain are different, so a whole gummy might feel like a lot at first, especially if you’re new to this. My advice? Start with half a gummy for your first couple of doses to test the waters. You can always bump it up to a whole gummy later if it feels too subtle.
Here’s how to ease into it:
First week: Cut a gummy in half (use a sharp knife or scissors, gummies can be sticky little jerks). Take that half in the morning on your “on” day, maybe with some breakfast so it doesn’t hit your stomach weird. Morning’s good because it can give you a nice lift for the day, and you’re less likely to feel any subtle effects keeping you up at night.
Pay attention: After you take it, jot down how you feel over the next few hours—any mood boost, focus, or maybe a bit of anxiety (it happens sometimes). If half feels good, stick with it for a week or two. If it’s too mild, try three-quarters of a gummy on your next dose day.
After a couple weeks: If you’re comfy with half or three-quarters and want to try the full gummy, go for it. Just don’t rush it—microdosing’s about finding that sweet spot where you feel enhanced but not “whoa, I’m noticing the walls breathing.”
Pro Tips for the Process
Set and setting: Even for microdosing, your mindset and environment matter. Take it on a day you’re feeling okay, not super stressed, and maybe when you’ve got some chill tasks or creative stuff planned. Avoid dosing before a big stressful meeting or something intense.
Stay consistent: Stick to the schedule for at least 4-6 weeks to get a sense of how it’s working. Some folks notice benefits (like better mood or less brain fog) after a few doses; for others, it’s more gradual.
Listen to your body: If you feel off, jittery, or just not into it, skip a dose or take a longer break. You can always pause for a week and restart. No pressure to keep going if it’s not vibing.
Hydrate and eat: P-cybin can make you feel a bit sensitive, so drink water and don’t skip meals. Some folks like to pair it with a little caffeine for an extra kick, but don’t overdo it.
Track it: Maybe keep a little notebook or phone note—nothing fancy, just “Took half gummy, felt focused but a bit spacey by noon” or whatever. Helps you dial in what works.
A Few Cautions (Like a Friend Looking Out)
Start low, go slow: A whole gummy is solid, but if you’re sensitive, even that could feel like a lot. Half a gummy is a safe bet to start.
Don’t mix with other stuff: Avoid alcohol or other substances on dose days, just to keep things clean and clear.
Check your headspace: If you’ve got a history of anxiety or mental health stuff, talk to a doc or therapist first. Microdosing’s not for everyone, and that’s cool.
Wrapping It Up
So, yeah, try the one-day-on, two-days-off schedule to start—maybe Monday, Thursday, Sunday as your dose days. Begin with half a gummy in the morning, see how it treats you, and tweak from there. Take it easy, keep a journal, and just enjoy the process of figuring out what works. It’s like tuning an instrument—you’ll find the right note with a little patience. Hit me up if you’ve got more questions or want to share how it’s going!
MACRODOSING
So, we're glad you’re vibing with the microdose plan! Alright, so you’ve got a solid microdosing routine going, and now you’re curious about stepping it up to a macrodose—that “heroic dose” territory of 4-5 grams of p-cybin. This is a whole different beast, so let’s talk it through and make sure you’re set for a good experience.
What’s a Heroic Dose?
A 4-5 gram dose of p-cybin is no joke—it’s what folks like Terence McKenna called a “heroic dose” because it can take you deep into your mind, with intense visuals, emotional insights, and sometimes straight-up mystical vibes. Since macro gummies are 0.50g each, you’re looking at 8-10 gummies to hit that 4-5g range. That’s a lot of gummies, so let’s break down how to approach this safely and intentionally after your microdose routine has you feeling comfortable.
Before You Dive In
Since you’ve been microdosing, you’ve probably got a sense of how p-cybin feels in small doses—mood lifts, maybe some clarity or creativity. A heroic dose is way more intense, so here’s how to prep like a pro:
Build on your microdose experience: Microdosing helps you get familiar with p-cybin’s effects, so you’re not going in blind. If you’ve been successfully microdosing for 4-6 weeks and feel good, you’re in a solid spot to consider a bigger dose. Make sure you’re comfortable with how your body and mind respond to smaller amounts first.
Tolerance check: P-cybin builds tolerance fast. If you’ve been microdosing, wait at least 1-2 weeks after your last microdose to reset your tolerance. Otherwise, 4-5g might not hit as hard as you expect, and you don’t want to waste the experience.
Mindset and timing: Pick a day when you’re feeling grounded, not stressed or dealing with heavy life stuff. A heroic dose can amplify emotions, so you want to go in with a clear head. Plan for a full 6-8 hours (plus recovery time), so no work or big plans that day.
The Schedule: When to Macrodose
Unlike microdosing, a heroic dose isn’t something you do regularly—it’s more like a once-in-a-while journey. After a good microdose routine, you might try a macrodose once every few months (think 2-6 months apart) to keep it special and avoid tolerance or emotional overload. Here’s how it fits with your microdosing:
Pause microdosing: Stop your microdose schedule for at least 1-2 weeks before the big dose. This gives your brain a reset and ensures the 4-5g hits properly.
Plan the macrodose: Pick a specific day for the heroic dose, then resume microdosing (if you want) no sooner than 1-2 weeks after to let your mind integrate the experience. Some folks take a longer break from all p-cybin to process what they learned.
How to Take It: Whole Gummies, Partial, and Easing In
Your gummies are 0.50g each, so 4-5g means 8-10 gummies. That’s a lot to chew through, and gummies can be heavy on the stomach, so here’s how to handle it:
Start low if you’re new to macrodosing: If you’ve only microdosed, jumping straight to 5g might be intense. Consider starting with a 2-3g dose (4-6 gummies) for your first bigger experience to get a feel for higher doses. If that goes well, you can try the full 4-5g next time. Think of it like leveling up gradually.
How to consume: Eating 8-10 gummies in one sitting could make you feel queasy, so here’s a plan:
Option 1: Eat over time: Break the dose into smaller chunks. For example, eat 5 gummies (1.25g) every 15-20 minutes over an hour until you hit your 4-5g target. This can ease the stomach load and make the come-up smoother.
Option 2: Make a tea: If you’re worried about chewing all those gummies, you can dissolve them in hot (not boiling) water to make a p-cybin tea. Crush or cut the gummies, steep them in warm water for 10-15 minutes, stir well, and drink slowly. Add some honey or ginger to make it tastier and settle your stomach. (Pro tip: Strain out any gummy bits if they gross you out.)
Empty stomach or light meal? A light meal 2-3 hours before can help avoid nausea but still let the p-cybin absorb well. Avoid heavy or greasy food.
Setting Up for Success
A heroic dose is a full-on journey, so you want to nail the set and setting:
Find a safe space: Do this at home or somewhere cozy and private where you feel 100% safe. Soft lighting, comfy blankets, and maybe some calming music (think instrumental or ambient playlists) can set the vibe. Have water, snacks (for later), and a notebook handy if you want to jot down thoughts.
Get a trip sitter: Even if you’re experienced, a trusted friend who’s sober and chill is a game-changer for a 4-5g dose. They don’t need to do much—just be there to reassure you if things get intense or help with practical stuff like getting you water.
Set an intention: Before you start, think about why you’re doing this. It could be “I want to explore my emotions” or “I’m looking for clarity on X.” An intention helps guide the experience, but don’t cling to it too hard—let the journey unfold.
Prepare for intensity: At 4-5g, expect strong visuals (like colors popping or patterns moving), deep emotional waves, and maybe some big existential thoughts. It can be beautiful, overwhelming, or both. Remind yourself it’s temporary (6-8 hours) and you’re safe.
During the Experience
Go with the flow: If it feels intense, breathe deeply and let the experience happen. Fighting it can make things feel heavier, so try to surrender to the ride.
Stay hydrated: Sip water or herbal tea. Avoid alcohol or caffeine, as they can mess with the vibe.
Have tools ready: Some people like to have art supplies, music, or nature sounds to engage with. Others just lie down and let their mind wander. Do what feels right.
If it gets tough: If you feel anxious, focus on your breath, remind yourself it’s just the p-cybin working, and lean on your trip sitter for grounding. Changing the music or moving to a quieter space can help.
After the Dose: Integration
A heroic dose can leave you with a lot to process—insights, emotions, or even just a sense of awe. Here’s how to wrap it up:
Rest and recover: You might feel wiped out the next day (sometimes called the “afterglow” or, if it’s rough, a bit of a “psychedelic hangover”). Eat nourishing food, sleep, and take it easy.
Reflect: Write down what came up during the experience. Even if it felt chaotic, there’s often wisdom in there that makes sense later.
Integrate: Talk to a friend, therapist, or journal about what you learned. A heroic dose can shift how you see things, so give yourself time to let it sink in before jumping back to microdosing.
Wait before repeating: Give yourself at least a month, if not longer, before another big dose. It’s not something to rush into again too soon.
Friendly Cautions
Know your limits: If microdosing felt edgy or you’ve got a history of mental health challenges (like anxiety, depression, or anything heavier), a heroic dose might be too much. Talk to a therapist or someone who knows psychedelics first.
Nausea is real: Eating 8-10 gummies can upset your stomach, so the tea method or spacing out the dose is your friend. Ginger tea or candies can help.
Respect the dose: 4-5g is powerful. If you’re not sure, start with 2-3g to get a feel for higher doses before going full heroic.
The Plan in a Nutshell
Prep: Pause microdosing for 1-2 weeks. Pick a calm day, set up a cozy space, and get a trip sitter.
Dose: Start with 2-3g (4-6 gummies) if it’s your first macrodose, or go for 4-5g (8-10 gummies) if you’re feeling ready. Eat them slowly or make a tea to avoid stomach issues. (Or eat the gummies normally and have Ginger tea to soothe the stomach)
During: Set an intention, let the experience unfold, and lean on your sitter if needed.
After: Rest, reflect, and wait at least 1-2 weeks before resuming microdosing. Space out heroic doses by months.
Schedule: Treat the macrodose as a one-off event every few months, not a regular thing.
You got this! A heroic dose can be profound if you go in with respect and prep. Have fun and stay safe!